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author：explore 2025-09-28 02:31:17 - browse：47659

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Hello, everyone. Damian here with the fallout from Pfizer’s downbeat update, a new entrant in obesity research, and an orthogonal CRISPR business.

The need-to-know this morning

Apellis Pharmaceuticals said a European advisory committee is expected to recommend against the approval of Syfovre, its eye drug for a common form of blindness. The company plans to appeal the negative ruling.
Sage Therapeutics and Biogen announced the commercial launch of Zurzuvae, an oral treatment for women with postpartum depression.
Merck and Moderna reported three-year follow-up data on their mRNA-based immunotherapy for advanced melanoma. Phase 3 studies are underway.
The FDA accepted Amgen’s marketing application for tarlatamab, a bispecific antibody to treat advanced small cell lung cancer. The approval decision date is June 12, 2024.

Is it time to worry about Moderna?

Yesterday’s news that Pfizer is expecting to sell far fewer Covid-19 vaccines than Wall Street expected sent shares of Moderna down as much as 6% on fears that the company could be in for a painful revision of its own.

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Wikipedia

The need-to-know this morning

Is it time to worry about Moderna?

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Tori Bowie and the unacceptable rates of Black maternal death

Parkland mass shooting to be reenacted for lawsuit

How to save PrEP access — and even expand it

'Cuddling' is just what the doctor ordered for a 200

Bright Health sells Medicare Advantage business to Molina

Medical schools are missing the mark on artificial intelligence

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Jesse Tyler Ferguson makes friendship bracelets for Taylor Swift's Eras Tour

FDA approval of Sarepta Duchenne genetic therapy gives me hope

FDA approves Recor Medical high blood pressure device

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Ambulance rides for just $100? Advisers want major billing fixes

Calls for Trump's election interference trial to be televised part of long debate

Free speech concerns arise in wake of journal editor Eisen's firing

Jesse Tyler Ferguson makes friendship bracelets for Taylor Swift's Eras Tour

Will General Catalyst be the first of many hospital takeovers?

Free speech concerns arise in wake of journal editor Eisen's firing

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