Wikipedia -WSS

Wikipedia

author：focus 2025-08-12 06:44:01 - browse：75

Several amyloid plaques forming between neurons in a brain — Amyloid plaques forming between neurons. Adobe

The Food and Drug Administration on Thursday granted full approval to the first therapy for Alzheimer’s disease clearly shown to slow the cognitive decline associated with the disease — a milestone in treatment, even if the benefits are modest.

The drug, called Leqembi, was developed by Eisai, the Japanese pharmaceutical company, and sold in partnership with Biogen. It previously secured conditional approval in January. The FDA’s decision will broaden patient access to the drug under the Medicare program and is likely to boost sales, even as Leqembi’s benefits and safety risks continue to be a source of debate.

Leqembi’s full, or traditional, approval was supported by results of a large clinical trial in which the drug slowed the rate of cognitive and functional decline by 27% compared to a placebo. Leqembi also beat placebo on a series of secondary measures of Alzheimer’s, and it had a dramatic effect on clearing toxic brain plaques called beta-amyloid, which play a role in the progression of the disease.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED Log In

Previous article： Medicare proposal to cover medical devices draws a mixed reaction
Next article： Biogen joins immunology wave with $1.15 billion acquisition of HI

explore

hotspot

WSS

5 wounded, 2 critically, in Michigan shopping center shooting

H5N1 virus can be tracked in retail milk, scientists say

Fla. should 'correct' controversial slavery curriculum: Republican Rep. Byron Donalds

9 mass shootings over the weekend rock US cities, leaving 5 dead, 56 injured

Bird flu surveillance in wastewater gets boost from consortium

Campaign finance charge dropped from case against Sam Bankman

explore

Wikipedia

hotspot

DIEP, the 'gold standard' of breast reconstruction, is under threat

Putin woos African leaders at a summit in Russia with promises of expanding trade and other ties

23andMe had bad news about my health. I wish a person had delivered it

China demands US invite Hong Kong leader to economic meeting, adding to strains over crackdown

Sports medicine is finally prioritizing gender equality

5 wounded, 2 critically, in Michigan shopping center shooting

Heart attack and stroke risk calculators need revising

Doctors increasingly discourage vaping amid mounting health concerns

Biden outlines 'new path' to provide student loan relief after Supreme Court rejection

Adidas to release second batch of Yeezy sneakers after breakup with Ye

hotspot

Investigation reveals sickle cell patients pressured into sterilizations

H5N1 virus can be tracked in retail milk, scientists say

Investigation reveals sickle cell patients pressured into sterilizations

Biden has enormous polling lead in Democratic primary, despite challenge from RFK Jr.

Many immigrants are left out of maternal health programs

Eyeing GLP

explore

Wikipedia

hotspot

explore