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                                      author：entertainment   
                                        
                                      
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          Under a microscope, human prostate cancer cells, colorized in blue, appear in an air bubble — coverage from STAT
          Under a microscope, human prostate cancer cells, colorized in blue, appear in an air bubble.																									Adobe
          An early-stage clinical trial of a radiopharmaceutical drug developed by Johnson & Johnson showed some signs of efficacy in prostate cancer patients, newly released data show, but four participants in the trial died.
          The drug, JNJ-6420, is designed to treat metastatic castration-resistant prostate cancer by delivering radioactive isotopes directly to cancer cells. Interest in such radiopharmaceuticals has skyrocketed following the approval of Pluvicto, which also treats prostate cancer.
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          In the Phase 1 data reported ahead of the American Society of Clinical Oncology meeting next week, 18% of participants on a mid-level dose of Johnson & Johnson’s treatment had a complete or partial response. For comparison, approximately 29.8% of the subjects in a Phase 3 trial of Pluvicto responded to the treatment.
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          Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.
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