knowledge -WSS

knowledge

author：fashion 2025-10-02 15:43:14 - browse：24

Under a microscope, human prostate cancer cells, colorized in blue, appear in an air bubble — coverage from STAT — Under a microscope, human prostate cancer cells, colorized in blue, appear in an air bubble. Adobe

An early-stage clinical trial of a radiopharmaceutical drug developed by Johnson & Johnson showed some signs of efficacy in prostate cancer patients, newly released data show, but four participants in the trial died.

The drug, JNJ-6420, is designed to treat metastatic castration-resistant prostate cancer by delivering radioactive isotopes directly to cancer cells. Interest in such radiopharmaceuticals has skyrocketed following the approval of Pluvicto, which also treats prostate cancer.

In the Phase 1 data reported ahead of the American Society of Clinical Oncology meeting next week, 18% of participants on a mid-level dose of Johnson & Johnson’s treatment had a complete or partial response. For comparison, approximately 29.8% of the subjects in a Phase 3 trial of Pluvicto responded to the treatment.

STAT+ Exclusive Story

Already have an account? Log in

This article is exclusive to STAT+ subscribers

Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

Already have an account? Log in

Monthly

$39

Totals $468 per year

$39/month Get Started

Totals $468 per year

Starter

$30

for 3 months, then $39/month

$30 for 3 months Get Started

Then $39/month

Annual

$399

Save 15%

$399/year Get Started

Save 15%

11+ Users

Custom

Savings start at 25%!

Request A Quote Request A Quote

Savings start at 25%!

2-10 Users

$300

Annually per user

$300/year Get Started

$300 Annually per user

View All Plans

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： State Dept. review finds Biden bears some blame for Afghanistan failures
Next article： Readout Newsletter: Parkinson's study, Gilead, CG Oncology

focus

WSS

Prior authorization reform is both possible and imperative

Man who had jail sentence commuted by Trump arrested again

Plane’s emergency slide plummets from sky, hits Chicago home

Stanford president to resign after investigation of research

Actors' union, Hollywood studios squabble over which side to blame as strike enters 5th day

TikTok cracks down on users posting about weight loss drugs

entertainment

knowledge

This article is exclusive to STAT+ subscribers

Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

hotspot

Activists slam private health insurers over coverage restrictions

Why some people catch Covid but never get sick

George Santos makes 1st court appearance after pleading not guilty to 13 counts

New warning issued for rebooking air travel after delays, cancellations

Sports medicine is finally prioritizing gender equality

Prior authorization reform is both possible and imperative

Biden outlines 'new path' to provide student loan relief after Supreme Court rejection

Medical experts are missing from AI regulatory conversations

The high cost of giving birth even with insurance

Russia strikes Ukraine's critical port facilities in Odesa after halting grain deal

explore

Researchers separate signal from noise in heart wearable data

To bolster infectious disease surveillance, genomics powerhouses team up

Man who had jail sentence commuted by Trump arrested again

Stanford updates investigation of president’s past research

India sets sights on home

The inclusion problem at the heart of rehabilitation research

explore

explore

focus

hotspot