fashion -WSS

fashion

author：leisure time 2025-10-02 22:40:12 - browse：437

Adam's take main illustration — Molly Ferguson/STAT

This week, I address pushback I received on my Novartis-MorphoSys column. But first, a preview of the expected readout from Gritstone Bio’s neoantigen cancer vaccine study.

A looming test for neoantigen cancer vaccines

Before the end of the quarter, Gritstone Bio will release preliminary results from a randomized, Phase 2 clinical trial investigating a personalized therapeutic cancer vaccine in microsatellite-stable colon cancer, a type of “immunologically cold” tumor that is resistant to immunotherapies like PD-1/PD-L1 inhibitors.

The Gritstone vaccine is designed to train a patient’s own T cells to recognize and kill cancer cells by targeting mutated cancer proteins, called neoantigens, that are unique to a patient’s own tumor. It’s a relatively new approach for cancer vaccines — made possible by powerful and relatively inexpensive genomic sequencing of tumors – that is intended to overcome all the previous failures in the field. Gritstone’s effort is also similar to one being used by Moderna and Merck that has reported encouraging results in melanoma — and is now being investigated in a Phase 3 study.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： BioMarin wins approval for gene therapy to treat hemophilia A
Next article： Chan Zuckerberg Biohub Chicago to focus on inflammation

Wikipedia

explore

WSS

Eye stem cell transplant could help restore vision in injured people

The pain doctors face in trying to build their families

Senate panel eyes new effort on drug shortages

Evacuations in place as 3 wildfires burn in eastern Washington state

Eye stem cell transplant could help restore vision in injured people

New details revealed about Purdue's marketing of OxyContin

focus

fashion

A looming test for neoantigen cancer vaccines

leisure time

The high cost of giving birth even with insurance

Chan Zuckerberg Biohub Chicago to focus on inflammation

The cancer drug shortage isn’t new — and neither are the solutions

Majority of Americans think Trump's Ga. election interference case is serious: POLL

Medicare details structure of new drug price negotiation program

Cancer drug shortages' outsize impact on ovarian cancer patients

Virginia high school admissions case could be legal follow

Special counsel raises new conflict of interest concerns for De Oliveira's lawyer

Cancer drug shortages should be causing more outrage

FDA approves first treatment for ultra

explore

An interview with Robert F. Kennedy Jr. on vaccines

Lung cancer is America's deadliest cancer. Yet so few get screened

Living with Hashimoto's and celiac disease, and med school, too

Special counsel raises new conflict of interest concerns for De Oliveira's lawyer

Ukraine taking heavy casualties 10 weeks into its counteroffensive

Stroke deaths set to near 10 million globally by 2050

Wikipedia

Wikipedia

explore

leisure time