leisure time -WSS

leisure time

author：leisure time 2025-10-02 22:40:01 - browse：95

Two people stare at a keyhole in a human head in between them, as the short-haired person on the left holds a key — first opinion coverage from STAT — Adobe

In many ways, psychiatry is still flying blind. People experiencing mental health conditions are prescribed various drugs until one (or a combination) finally works — a painful process that can take years. As a psychiatrist and neuroscientist, I became increasingly impatient and frustrated with this ineffective way of treating patients. This guided the core question behind my research: Can biology explain how people with the same psychiatric disorder respond differently to the same treatment?

Since I first began exploring this question more than a decade ago, mental illness has become a global epidemic. Despite significant efforts, progress in psychiatric drug development has remained disappointingly slow. There have been a few notable approvals in recent years, and a renewal of interest by Big Pharma, following a retreat from psychiatric research in the mid to late 2000s. But the landscape remains predominantly marked by failures and a dry drug development pipeline. Approved drugs follow the same pattern of prescribing via guesswork, with most patients not responding to a given drug. This cycle of trial-and-error drug development producing trial-and-error treatment arises from a simple source: We have not systematized a process for learning from our failures and successes.

Related: A ‘renaissance in neuroscience’ could deliver a fresh crop of psychiatric medicines

For example, take depression: While the rise of selective serotonin reuptake inhibitors (SSRIs) in the 1980s and 1990s seemed to provide a solution, seminal studies in the 2000s exposed fundamental limitations of our treatment options. Antidepressants are widely prescribed, but their efficacy relative to placebo is modest.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Tori Bowie and the unacceptable rates of Black maternal death
Next article： Wegovy trial has doctors encouraged over new possibilities

WSS

Drastic changes should bring profitability, startup health insurers say

Twitch streamer Kai Cenat speaks out for 1st time since causing mayhem with Union Square giveaway

7 people shot in DC, police say

NIH trials fail to test meaningful long Covid therapies, experts say

Brain 'hot spot' may explain why African Americans feel greater pain

Listen: Merck v. USA, the best of ASCO, and Leqembi at the FDA

explore

leisure time

Related: A ‘renaissance in neuroscience’ could deliver a fresh crop of psychiatric medicines

hotspot

Continuity nursing helped my family in our darkest PICU moments

Maui's cultural, historic landmarks damaged in the devastating wildfires

Hollywood unions extend contract negotiations for actors

FDA panel issues narrow recommendation for Covid vaccine booster doses

New Eli Lilly Alzheimer’s data poses Medicare coverage conundrum

A biotech analyst on neuroscience, placebo effect, not over

ChatGPT in medicine: STAT answers readers' burning questions

Brain 'hot spot' may explain why African Americans feel greater pain

Sports medicine is finally prioritizing gender equality

Doctor appointment wait times are getting worse

entertainment

Can food be medicine? And other questions about a new push

Inside the fall of star MIT scientist David Sabatini

In same hospitals, Black patients receive fewer opioids than white patients

7 people shot in DC, police say

Wayne Brady comes out as pansexual: 'Free to love whomever I want'

Van's Gluten Free Original Waffles recalled for possible wheat allergen

Wikipedia

Wikipedia

leisure time

hotspot