Wikipedia -WSS

Wikipedia

author：fashion 2025-10-02 19:19:57 - browse：71612

Adam's take main illustration — Molly Ferguson/STAT

The Food and Drug Administration should halt Cassava Sciences’ ongoing clinical trials in Alzheimer’s disease. That, and other thoughts on the fallout from the City University of New York investigation that raised serious doubts about the science underpinning the company’s experimental drug simufilam.

Patient safety is paramount to the FDA, so stopping Cassava’s two Phase 3 studies is the ethically correct thing to do.The FDA has the power to place clinical holds on experimental drugs when there’s evidence of an unacceptable safety risk to study participants. Simufilam doesn’t appear to be toxic. It’s not causing dangerous side effects. But study participants can also be harmed when they volunteer for a clinical trial based on false or misleading information about a drug’s potential efficacy.

The CUNY committee charged with investigating Cassava’s principal scientific collaborator, the neuroscientist Hoau-Yan Wang, could not definitively prove that Wang faked simufilam data, but that’s only because he refused to turn over original data and primary research records that the committee had requested to examine. Wang also claimed that boxes of research records relevant to the investigation were thrown away. The investigative report was first made public last week in the journal Science.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： In Memoriam: Notable people who died in 2023
Next article： Can sheer will power keep patients alive in their dying hours?

WSS

Telehealth for opioid use disorder is lifesaving

What STAT readers think about the FDA and patient advocacy

Three trends to watch in biotech in 2024

Pig kidney works a record two months in donated body

Long Covid needs a new name — and a new frame

Keeping primary care docs in field isn't impossible, says AAFP CEO

focus

Wikipedia

entertainment

Food as medicine: CMS rules hamper 'prescribing' of fruits, veggies

FDA approves updated Covid vaccines

FDA approval of Sarepta Duchenne genetic therapy gives me hope

Medicare drug price negotiation hasn't dried up venture capital

Sports medicine is finally prioritizing gender equality

Why health care costs have stayed mostly flat since 2010

Bright Health sells Medicare Advantage business to Molina

Drinking less cuts risk of oral cavity, esophageal cancer: Report

Jerome Adams on the need for new antivirals for Covid

Hospitals consider fixing cancer drug shortages on their own

hotspot

WATCH: Why do bright lights make us see spots?

SEC charges former device maker CEO with $41 million fraud

Three trends to watch in biotech in 2024

Violet CEO on training clinicians to promote more inclusive care

FDA proposes changes to key medical devices approval pathway

Editas, Vertex strike deal on CRISPR

focus

focus

focus

Wikipedia