Wikipedia -WSS

Wikipedia

author：fashion 2025-10-01 23:04:54 - browse：337

Travere Therapeutics said Thursday that a study meant to confirm the benefit of its newly approved drug for a rare kidney disorder narrowly failed.

In the trial, 404 patients with the disorder, IgA nephropathy, were randomized to receive either Travere’s daily pill, Filspari, or irbesartan, a decades-old blood pressure drug often used to help manage the disease. Early data had showed the drug cut protein levels in the urine, a biomarker of kidney function, by half after nine months. That convinced regulators to give Filspari accelerated approval in February, pending full results using a more direct measure of kidney function.

The new data, after 24 months, showed that patients who received Filspari declined less quickly than those in the control group. But the results just missed statistical significance, with a P value of 0.058.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Anesthesiologist group: stop taking Ozempic before surgery
Next article： Alabama IVF ruling threatens families facing fatal genetic disease

WSS

Ed Silverman on new gene therapies, biosimilars, coffee, and more

TB outbreak tied to bone grafts underscores testing shortcomings

O'Shea Sibley was killed after expressing queer joy by voguing, activists say

Cyberattack on UnitedHealth subsidiary cripples pharmacies, hospitals

Why palliative psychiatry is worth discussing

Why palliative psychiatry is worth discussing

focus

Wikipedia

focus

Hepatitis C has a cure — but many Americans still lack access to it

Trump, Nauta plead not guilty to new classified docs charges but De Oliveira still not arraigned

The high cost of giving birth even with insurance

A solution to the after

Anesthesiologist group: stop taking Ozempic before surgery

Novo acquires Inversago for up to $1 billion

The high cost of giving birth even with insurance

PBM reform efforts get punted in Congress

What does generative AI mean for health care? We asked experts

After John Oliver segment, STAT readers share their opioid

knowledge

Listen: Your guide to Wegovy's blockbuster heart study

PBM reform efforts get punted in Congress

A new nitrogen execution bill also undermines medical licensing

Genentech weighs delaying cancer therapy after drug pricing law

The perfect storm of weather conditions that led to the devastating wildfires in Maui

Obesity drugs seen as possible treatment for liver disease MASH

focus

entertainment

focus

hotspot