leisure time -WSS

leisure time

author：explore 2025-10-01 22:58:30 - browse：35

Babies born by in vitro fertilization — when a woman’s egg is fertilized outside of her body and then implanted back into her uterus — skew more heavily male than babies conceived naturally. A study published Monday in the Proceedings of the National Academy of Sciences sheds light on why that happens.

You’ll want to know:

During normal development, female embryos usually shut down the activity of one of their two X chromosomes to keep gene expression levels the same as in male embryos. But researchers at the China Agricultural University saw that this process often went awry in mouse embryos created by IVF. Those female embryos were defective and didn’t develop properly. Researchers said it might be possible to fix the problem by adding a particular chemical (a derivative of vitamin A) to embryos in the lab dish before they’re implanted.

The background:

More than 5 million people have been born using IVF since it was pioneered in 1978. Skewed sex ratio has been debated for decades; one 2010 study found IVF produced as many as 128 boys born for every 100 girls.

Keep in mind:

The study was carried out on IVF embryos in mice, with naturally conceived mouse embryos as the control group. While mice are a commonly used research subject, findings in rodents don’t always translate directly to the biology of humans.

Also note that IVF births account for just 1 to 2 percent of total births in the United States, so having more males born via fertility treatments is unlikely to affect the gender ratio of babies nationwide. “I don’t think anyone should be worried even if there’s a slight increase in male births in patients undergoing fertility care,” said Dr. Mark Sauer, an obstetrician and gynecologist at Columbia University Medical Center, who was not involved in the study.

The bottom line:

Scientists might have figured out the cause for the skewed sex ratio that shows up in IVF births, but it’s not clear yet whether the strategies they propose to fix the issue will work in practice.

Previous article： State Dept. review finds Biden bears some blame for Afghanistan failures
Next article： Readout LOUD podcast: What to know about H5N1 bird flu

WSS

Use wet bulb globe temperature, not heat index, to protect workers

Apple Watch's A

Google says AlphaFold 3 can map a vast universe of biomolecules

Sanofi to acquire U.S. biotech Inhibrx in $2.2 billion deal

Google says AlphaFold 3 can map a vast universe of biomolecules

Software glitch causes Tandem insulin pump to shutdown, FDA warns

hotspot

leisure time

You’ll want to know:

The background:

Keep in mind:

The bottom line:

focus

New Eli Lilly Alzheimer’s data poses Medicare coverage conundrum

It shouldn't be easy to buy synthetic DNA to recreate a deadly virus

As demand for Covid shots wanes, Moderna seeks its next success

Elevance, private equity launch primary care company

FDA approval of Sarepta Duchenne genetic therapy gives me hope

Dog Aging Project founders on what lies ahead after losing funding

How to save PrEP access — and even expand it

CVS is on a mission to consolidate health care. Will it work?

ChatGPT in medicine: STAT answers readers' burning questions

Head of FDA's diagnostics center, who led through Covid, retires

hotspot

There's an unseen cost to disruptive road

Medicare says breakthrough device reimbursement rule to come by summer

FDA sets aggressive timeline for overhauling inspection procedures

Dana Farber says 6 studies to be retracted and 31 corrected

To bolster infectious disease surveillance, genomics powerhouses team up

Brain worms: The science behind RFK Jr.'s parasitic infection

hotspot

Wikipedia

focus

leisure time