hotspot -WSS

hotspot

author：knowledge 2025-09-29 14:23:39 - browse：93234

Blue CAR-T cell attacks a leukemia cell. --health coverage from STAT — Engineered receptors on the surface of a T-lymphocyte bind to a leukemia cell. Adobe

The announcement on Tuesday that the Food and Drug Administration was investigating whether CAR-T immunotherapy had itself caused blood cancers initially appeared to be a significant blow to one of the brightest spots in cancer care.

But experts quickly cautioned that risk of this complication is probably minuscule compared to the known risk of secondary cancers from other cancer therapies like chemotherapy and radiation. They noted that CAR-T cells are immune cells that are genetically engineered to fight cancer, and that such genetic modifications were long thought to carry a risk of causing a second, new cancer in patients. The surprise, in a way, is that since CAR-T was first invented more than 10 years ago, that risk had remained just theoretical.

“There’s been a requirement for long-term follow up. I think this is why we’re all surprised. As far as I think any one of us knew, it’d never happened with any of the FDA-approved CAR-Ts,” said Marcela Maus, a cell therapy researcher at Mass General Cancer Center.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Medical leaders decry Supreme Court decision on affirmative action
Next article： Medical devices makers are asking for forgiveness, not permission

WSS

Achieving telehealth equity for people with hearing loss

Surgeons perform first xenotransplant using CRISPR'd pig kidney

Richard Slayman had a rejection episode of his pig kidney before leaving hospital

Biotech investment managers search for lucrative opportunities

Erich Jarvis studies song birds to learn about human stuttering

Guardant Health colon cancer test endorsed by FDA advisory panel

explore

hotspot

entertainment

Duchenne breakthrough therapy leaves behind pioneering families

What Kate Middleton's cancer revelation might teach the world

Sports medicine is finally prioritizing gender equality

Pfizer, Moderna say biotech, pharma drug development is a sprint

Biden outlines 'new path' to provide student loan relief after Supreme Court rejection

Duchenne drug from Nippon Shinyaku fails in rare confirmatory trial

Trump demands the U.S. pay no more for drugs than other countries … again

The HPV vaccine prevents cancer in men, too. Why do so few people get it?

FDA approval of Sarepta Duchenne genetic therapy gives me hope

Some medical students still think black patients feel less pain

entertainment

Readout LOUD podcast, live from the STAT Breakthrough Summit East

Cancer, immunology, HIV research ensnared in fetal tissue politics

Lawsuit challenges CMS nursing home minimum staffing rule

Decentralized clinical trials need collaboration to achieve wider use

Chinese researcher claims birth of first gene

Hospitals need to get ahead of regulations on climate change

explore

Wikipedia

Wikipedia

leisure time