knowledge -WSS

knowledge

author：entertainment 2025-09-30 22:05:13 - browse：237

Alzheimer’s disease has killed at least three women in Astrida Schaeffer’s family over two generations, leaving her feeling helpless and bereft.

The first was her Polish-born maternal grandmother, who began showing symptoms when Schaeffer started college in 1981 and died seven years later. Then came her mother, a onetime Fulbright Scholar and high school language teacher who had been fluent in five languages but lost the ability to speak. She died in 2019. Last year, the disease killed Schaeffer’s mother’s sister, a former lab technician for Johnson & Johnson.

Schaeffer, a 59-year-old costume historian in North Berwick, Maine, has no symptoms of Alzheimer’s. But in 2021 her family history led her to apply to join a clinical trial testing a drug on people at risk for developing them. To participate, volunteers couldn’t have cognitive impairment. But they needed to test positive for a biomarker that put them at higher risk for mental decline ― deposits of a sticky toxic protein in the brain called beta-amyloid that is a hallmark of the disease.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Moonlake's readout produced a cash windfall. Risks remain
Next article： Scientists find bacteria from stomach of ancient iceman

focus

hotspot

WSS

'Cuddling' is just what the doctor ordered for a 200

HHS secretary Becerra pressed on Change HealthCare cyberattack

Medical schools are missing the mark on artificial intelligence

Jailed Russian opposition leader Alexey Navalny gets 19 more years in prison

Parkland mass shooting to be reenacted for lawsuit

Acadia's Nuplazid fails as schizophrenia medicine in Phase 3 study

knowledge

knowledge

hotspot

Sports medicine is finally prioritizing gender equality

Prosecutors seek bail revocation for FTX founder Sam Bankman

Activists slam private health insurers over coverage restrictions

Medicare coverage of Wegovy, once blocked, now looks possible

Drug repurposing or repositioning? The language matters

R.J. Reynolds sues to protect 'crisp' cigs from California flavor ban

Food as medicine: CMS rules hamper 'prescribing' of fruits, veggies

Amylyx ALS drug fails trial: Relyvrio patients react with fear, worry

Guidelines to prevent youth baseball injuries need more muscle

Flash flooding emergencies prompt evacuations in Kentucky, Tennessee

hotspot

In boost for rare disease push, AstraZeneca to buy Amolyt Pharma

EPA limits use of carcinogenic gas for sterilizing medical devices

Judge in Trump's Jan. 6 case gives attorneys 2 weeks to propose trial date

Pediatricians' group reaffirms support for gender

Does Medicare's free annual wellness visit do any good?

Jesse Tyler Ferguson makes friendship bracelets for Taylor Swift's Eras Tour

hotspot

focus

hotspot

entertainment