explore -WSS

explore

author：Wikipedia 2025-09-28 23:48:43 - browse：7562

Blue CAR-T cell attacks a leukemia cell. --health coverage from STAT — Engineered receptors on the surface of a T-lymphocyte bind to a leukemia cell. Adobe

The announcement on Tuesday that the Food and Drug Administration was investigating whether CAR-T immunotherapy had itself caused blood cancers initially appeared to be a significant blow to one of the brightest spots in cancer care.

But experts quickly cautioned that risk of this complication is probably minuscule compared to the known risk of secondary cancers from other cancer therapies like chemotherapy and radiation. They noted that CAR-T cells are immune cells that are genetically engineered to fight cancer, and that such genetic modifications were long thought to carry a risk of causing a second, new cancer in patients. The surprise, in a way, is that since CAR-T was first invented more than 10 years ago, that risk had remained just theoretical.

“There’s been a requirement for long-term follow up. I think this is why we’re all surprised. As far as I think any one of us knew, it’d never happened with any of the FDA-approved CAR-Ts,” said Marcela Maus, a cell therapy researcher at Mass General Cancer Center.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： In age of alternative facts, a scholarly course on calling out crap
Next article： The creative science of coining drug names

hotspot

leisure time

WSS

Extensive review finds private equity owners jack up cost of care

Judge denies Trump's request for new trial in E. Jean Carroll case

Readout Newsletter: PTC, Dyne, Rapport, Cytokinetics news

Empower primary care with adequate payments and technology

Crowdfunding for medical bills sidesteps core problem, author says

Can gargling with Listerine treat gonorrhea of the mouth?

hotspot

explore

focus

ChatGPT in medicine: STAT answers readers' burning questions

PBM executives asked to testify by House panel

Wildfire smoke exposes gaps in outdoor worker protections

GSK’s asthma push continues as drug succeeds in Phase 3 trials

Tori Bowie and the unacceptable rates of Black maternal death

AltruBio raises $225 million to develop ulcerative colitis drug

Virginia high school admissions case could be legal follow

Welsh Carson private equity firm escapes from FTC antitrust case

Virginia high school admissions case could be legal follow

Are infertility treatments 'essential' during the Covid

leisure time

HHS's proposed rule does nothing to address the climate crisis

Welsh Carson private equity firm escapes from FTC antitrust case

How a Boston hospital is priming medical residents to use GPT

Has Bernie Sanders reached the limit of his pharma bullying effort?

A woman pleads guilty to fire that kept a Wyoming abortion clinic from opening for a year

5 dead in mass shooting on Caribbean island of St. Vincent: Police

focus

hotspot

leisure time

entertainment