focus -WSS

focus

author：entertainment 2025-09-30 16:27:19 - browse：48

On Tuesday, Google DeepMind and Isomorphic Labs announced a significant progress update on the next iteration of AlphaFold, the deep learning model that in 2020 cracked the problem of predicting a protein’s structure from its amino acid sequence, leapfrogging other approaches in computational biology.

Now, the companies say they have developed the model to predict not just standalone protein structures, but what proteins look like in combination with several classes of molecules, including small molecules and nucleic acids — capabilities that are key for drug development.

“We really needed to make progress on protein-ligand binding and co-folding of ligands with proteins in order to help us design more effective drugs,” said Demis Hassabis, CEO of both DeepMind and Isomorphic Labs, which spun out in 2021 with the goal of applying deep learning approaches to drug discovery. The updated model can also predict protein structures after they’ve been modified. “Basically the new AlphaFold can cope with all of these different things, which is pretty amazing.”

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Walensky prepares to leave CDC — and Congress — behind
Next article： Listen: Biogen's messy board & Laronde's data problem

focus

WSS

Study points to new risk in gene therapy death of Terry Horgan

These geoengineering technologies could help combat the climate crisis, scientists say

Health insurers' Q3 question: how much care are people getting?

WHO recommends second malaria vaccine

The Karikó problem: Lessons for funding basic research

The United States is paying nearly triple for new Covid vaccines

leisure time

focus

knowledge

FDA approval of Sarepta Duchenne genetic therapy gives me hope

CDC picks Alphabet's Verily for wasterwater surveillance contract

ChatGPT in medicine: STAT answers readers' burning questions

Option Care buys Amedisys in $3.6 billion home care deal

Anesthesiologist group: stop taking Ozempic before surgery

4 killed, 7 hurt in mass shooting at July 4 block party in Louisiana; no arrests made

Anesthesiologist group: stop taking Ozempic before surgery

Lawsuit highlights wrinkle for disputes over surprise medical bills

The Supreme Court will review a ruling striking down a domestic violence federal gun ban

Study points to new risk in gene therapy death of Terry Horgan

focus

Russia says it foiled Ukrainian drone attack on Moscow as Kyiv's counteroffensive grinds on

Brain 'hot spot' may explain why African Americans feel greater pain

Inside the fall of star MIT scientist David Sabatini

Grail is spending more than ever lobbying Congress

New oral drug delivery patch is modeled after octopus tentacles

Stop Congress from blocking public access to science

entertainment

focus

focus

focus