hotspot -WSS

hotspot

author：explore 2025-09-30 00:45:59 - browse：1

Adam's take main illustration — Molly Ferguson/STAT

This week, a preview of the TUDCA study in ALS and thoughts on how it might impact Amylyx Pharmaceuticals. Also, I chatted with CRISPR Therapeutics CEO Sam Kulkarni about its new investor. Read to the end for some burning questions, random thoughts.

The next ALS data readout — overdue but important

A European academic consortium is expected to announce results soon from a clinical trial investigating the use of a widely available nutritional supplement called tauroursodeoxycholic acid, or TUDCA, in people living with ALS. The outcome of the TUDCA-ALS study could have implications for Amylyx Pharmaceuticals, because TUDCA is one of the two main ingredients in Relyvrio, the company’s approved drug for ALS.

In a recent interview at Amylyx’s Kendall Square headquarters, co-CEOs Justin Klee and Josh Cohen mostly downplayed the suggestion that results from the randomized, placebo-controlled TUDCA study might affect Relyvrio negatively, or even positively.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Medical records are filled with copy
Next article： RaDonda Vaught to speak at CommonSpirit event on patient safety

WSS

Ford recalls 870K F

VC firm RA Capital starts a new synthetic biology incubator

Medical device lobby: We're tired of waiting on Medicare coverage

In search for therapies for solid tumors, companies turn to claudin

Kristina Burow of ARCH Venture Partners shares her next big bets STAT

Biden announces an advanced cancer research initiative

knowledge

hotspot

The next ALS data readout — overdue but important

hotspot

Medical records are filled with copy

Congress gives doctors Medicare pay bump

Medical leaders decry Supreme Court decision on affirmative action

House looks to weaken Medicare negotiation

Moonlake's readout produced a cash windfall. Risks remain

An inside look at PIPEs, biotech's buzzy new financing tool

Heart attack and stroke risk calculators need revising

How to fix the rural physician shortage in the U.S.

New air purifier tech could be key to improving indoor air quality

Kenai launches with $82 million for Parkinson’s stem cell therapy

focus

Congress gives doctors Medicare pay bump

Ending health disparities requires full federal government, panel says

RaDonda Vaught to speak at CommonSpirit event on patient safety

Trump lawyers meet with special counsel in Jan. 6 case as potential indictment looms

Behind warning on Apellis’s eye drug lies a conflict of interest

Marc Tessier

focus

knowledge

hotspot

hotspot