focus -WSS

focus

author：knowledge 2025-09-28 23:48:23 - browse：9172

Neumora, a privately held biotech company, is moving into the final phase of testing with a novel treatment for depression that showed promise in a mid-stage trial.

The drug, a daily pill called navacaprant, led to statistically significant improvements over placebo on a measurement of disease severity for patients with moderate to severe major depressive disorder, Neumora said Tuesday. In the eight-week study, the medicine also led to improvements in patient-reported anhedonia, a reduced ability to experience pleasure that often accompanies severe depression.

Navacaprant’s statistically significant benefits came from a pre-specified subset of 100 patients in a study that enrolled 171 people. In the total population, including 71 patients who had mild to moderate disease, navacaprant’s effect on depressive symptoms was numerically superior to placebo but did not reach the threshold of statistical significance, missing the study’s primary endpoint.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED Log In

Previous article： Psychedelics group wrestles with new pharma identity
Next article： Resistance to cancer drugs: A new genetic explanation

hotspot

WSS

Trump got a 'target letter.' What is one and what does it mean?

Divers poised to search for children washed away in Pennsylvania flash flood

Awakening the world to the whoosh: A patient's crusade

Celebrate National Dole Whip Day for 3 days this week at Disney

Celebrate National Dole Whip Day for 3 days this week at Disney

Public funding for King Charles III and royals has been recalculated due to windfarm deal profits

focus

focus

hotspot

23andMe had bad news about my health. I wish a person had delivered it

TikTok cracks down on users posting about weight loss drugs

After affirmative action ruling, medical educators look to 'holistic review'

Tesla recalling nearly 16,000 of its 2021

Supreme Court strikes down use of affirmative action

DeSantis talks Trump, trans issues and 'what wokeness is'

Malaria cases in Florida and Texas: Here’s what you need to know

Russia strikes Ukraine's critical port facilities in Odesa after halting grain deal

Guidelines to prevent youth baseball injuries need more muscle

Russia strikes Ukraine's critical port facilities in Odesa after halting grain deal

explore

India sets sights on home

Plane’s emergency slide plummets from sky, hits Chicago home

Judge rejects Trump's request to move Stormy Daniels hush

Public funding for King Charles III and royals has been recalculated due to windfarm deal profits

Jury awards Florida girl burned by McDonald's Chicken McNugget $800,000 in damages

A Q&A with Gavi’s Seth Berkley on vaccines, Covid, and more

entertainment

hotspot

hotspot

focus