Wikipedia -WSS

Wikipedia

author：explore 2025-09-27 17:03:02 - browse：3

Representative fluorescent multiplex immunohistochemistry colorful staining of healthy human colon. -- cancer coverage from STAT — Staining reveals different immune cells in a healthy human colon. Courtesy Olivia Newton-John Cancer Research institute

Within the linings of our guts, immune cells patrol like sentries on a castle wall. These cells, called intraepithelial T lymphocytes, are constantly probing the cells of the gut barrier for signs of disease, killing any cells that appear suspect due to infections or cancer mutations.

A new paper published in Science Immunologyon Friday suggests that a subtype of T cells called gamma-delta T cells may be key to that process — and that a protein known as TCF-1 is central to controlling their actions. The work, led by Australian researchers, helps unlock the long underappreciated role of these cells in cancer defense and could open new directions for developing immunotherapies for colorectal cancer, immunologists said.

Gamma-delta T cells have been “largely understudied” compared to their immune counterparts, alpha-beta T cells, said Ana Carrizosa Anderson, a cancer researcher at Harvard University who did not work on the study. “This study certainly helps cement the role of gamma-delta T cells in colon malignancy,” she said. “I think it provides a foundation for building understanding of some basic biology or some therapeutic approaches.”

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Hepatitis C has a cure — but many Americans still lack access to it
Next article： Plastic surgeons increase patient psychiatric screenings

focus

WSS

CDC wastewater surveillance dashboard to track bird flu hotspots

Medicare says breakthrough device reimbursement rule to come by summer

Shionogi licenses Pompe disease therapy from Maze Therapeutics

5 to watch: Tech startups trying to solve health care's staffing crisis

Use wet bulb globe temperature, not heat index, to protect workers

Software glitch causes Tandem insulin pump to shutdown, FDA warns

Wikipedia

Wikipedia

entertainment

In Memoriam: Notable people who died in 2023

SCOTUS questions limit to govt efforts to fight misinformation

After affirmative action ruling, medical educators look to 'holistic review'

5 to watch: Tech startups trying to solve health care's staffing crisis

ChatGPT in medicine: STAT answers readers' burning questions

Future doctors should be trained to promote social change

Drug repurposing or repositioning? The language matters

5 to watch: Tech startups trying to solve health care's staffing crisis

Trump demands the U.S. pay no more for drugs than other countries … again

SCOTUS questions limit to govt efforts to fight misinformation

Wikipedia

Intermittent fasting comes with a heart risk? Not so fast

Readout Newsletter: Sanofi, Novavax, Maze x Shionogi news

Study: People of West African ancestry at greater risk of cardiac amyloidosis

Future doctors should be trained to promote social change

U.K. researchers warn about biases in medical devices, algorithms

Bird flu outbreak in cows is latest avian flu curveball

focus

focus

leisure time

focus