comprehensive -WSS

comprehensive

author：hotspot 2025-09-28 01:37:10 - browse：72895

Stoke Therapeutics is still seeking an effective dose for an experimental drug to treat a severe form of childhood epilepsy, following the release of updated data Tuesday that showed disappointing reductions in convulsive seizure activity.

In the latest look at an ongoing mid-stage study, three monthly injections of the Stoke drug, called STK-001, given at a 45-mg dose, resulted in a median 18% reduction in convulsive seizure activity, compared to baseline.

The new analysis was conducted on 16 children diagnosed with a rare form of epilepsy called Dravet syndrome. Last November, in six patients, the drug showed a median 55% reduction in seizure activity.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED Log In

Previous article： New Eli Lilly Alzheimer’s data poses Medicare coverage conundrum
Next article： European regulators consider appeal over Amylyx ALS drug

knowledge

WSS

How clinical AI models' predictive power can degrade over time

Bird flu outbreak in cows is latest avian flu curveball

Readout LOUD podcast: Merger Mondays, Ozempic panic

How clinical AI models' predictive power can degrade over time

Akero's treatment for NASH falls short in cirrhosis study

It shouldn't be easy to buy synthetic DNA to recreate a deadly virus

hotspot

comprehensive

explore

Medical leaders decry Supreme Court decision on affirmative action

A fraught question for the kids of Alzheimer’s: Is it coming for us?

Dobbs anniversary: the lost opportunity of abortion as health care

After gene therapy, two congenitally deaf children hear for the first time

As demand for Covid shots wanes, Moderna seeks its next success

Takeaways from AdvaMed, the largest medical devices conference

Moonlake's readout produced a cash windfall. Risks remain

Peter Marks talks Operation Warp Speed for Rare Diseases

New air purifier tech could be key to improving indoor air quality

What's changing in Medicare's open enrollment this year?

focus

Kidney disease boosts cardiac arrest risk for Hispanics, Latinos

After gene therapy, two congenitally deaf children hear for the first time

What nurses really want: sufficient staffing for patient care

Eight reasons why you should get an updated Covid vaccine

How doctors and nurses shape Google's AI

Steward Health Care files for bankruptcy

knowledge

entertainment

hotspot

hotspot