Wikipedia -WSS

Wikipedia

author：hotspot 2025-09-27 12:49:05 - browse：9

Representative fluorescent multiplex immunohistochemistry colorful staining of healthy human colon. -- cancer coverage from STAT — Staining reveals different immune cells in a healthy human colon. Courtesy Olivia Newton-John Cancer Research institute

Within the linings of our guts, immune cells patrol like sentries on a castle wall. These cells, called intraepithelial T lymphocytes, are constantly probing the cells of the gut barrier for signs of disease, killing any cells that appear suspect due to infections or cancer mutations.

A new paper published in Science Immunologyon Friday suggests that a subtype of T cells called gamma-delta T cells may be key to that process — and that a protein known as TCF-1 is central to controlling their actions. The work, led by Australian researchers, helps unlock the long underappreciated role of these cells in cancer defense and could open new directions for developing immunotherapies for colorectal cancer, immunologists said.

Gamma-delta T cells have been “largely understudied” compared to their immune counterparts, alpha-beta T cells, said Ana Carrizosa Anderson, a cancer researcher at Harvard University who did not work on the study. “This study certainly helps cement the role of gamma-delta T cells in colon malignancy,” she said. “I think it provides a foundation for building understanding of some basic biology or some therapeutic approaches.”

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： BioMarin wins approval for gene therapy to treat hemophilia A
Next article： IVG is promising — but it won’t replace IVF quite yet

hotspot

knowledge

WSS

Cancer, immunology, HIV research ensnared in fetal tissue politics

Chinese researcher claims birth of first gene

Flu, Covid vaccination rates decline, new survey data show

Bring on the sabbaticals for nurses

The United States is paying nearly triple for new Covid vaccines

Nobel honors Karikó and Weissman's enduring partnership

hotspot

Wikipedia

hotspot

DIEP, the 'gold standard' of breast reconstruction, is under threat

Asbestos ban is immediate, but health effects will linger for decades

Trump demands the U.S. pay no more for drugs than other countries … again

Lawsuit highlights wrinkle for disputes over surprise medical bills

At least 13 dead in Texas as scorching temps continue

CRISPR base editing slashes cholesterol levels in monkeys

After affirmative action ruling, medical educators look to 'holistic review'

Congress extends some pandemic preparedness programs

Supreme Court strikes down use of affirmative action

Flu, Covid vaccination rates decline, new survey data show

leisure time

Readout Newsletter: Biotech news, Wall Street disappointment, Lilly's drug delays

The stability of $0 premiums in Medicare Advantage

RSV injection headlines need to be accurate for good uptake

Medicare innovation center doesn’t save money, experts say

Yancopoulos of Regeneron works to expand Dupixent success

What Kate Middleton's cancer revelation might teach the world

explore

hotspot

knowledge

leisure time