Wikipedia -WSS

Wikipedia

author：entertainment 2025-09-27 09:53:32 - browse：2625

Medical illustration of Streptococcus pneumoniae bacteria — A medical illustration of drug-resistant, Streptococcus pneumoniae bacteria. Antibiotic Resistance Coordination and Strategy Unit/CDC

Micronoma, a San Diego-based biotech startup, was founded on the idea that signatures from microbes that colonize tumors could lead to a blood test to detect cancer. The hypothesis was based on a high-profile Nature paper, published in 2020, that suggested these microbes are consistently found in tumors, and that they create such specific signatures they could be used to identify cancer types with nearly 100% accuracy.

But late Monday night, a team of researchers published a manuscript on the preprint site bioRxiv.com showing what they believe to be two “fatal errors” in the Nature paper’s analyses, invalidating not only the paper’s findings but possibly the scientific foundation for Micronoma, which has raised an estimated $17.5 million in funding from investors including SymBiosis Capital Management and the Seerave Foundation.

One allegation is that the Nature paper’s authors didn’t adequately filter out human DNA from their database of tumor samples, leading them to incorrectly classify millions of human sequences as bacterial. The other is that a separate error led the team’s algorithm to find false associations between specific microbial signatures and cancer types.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED Log In

Previous article： Psychedelics group wrestles with new pharma identity
Next article： 3 killed, 8 injured in late

hotspot

WSS

Churchill Downs extends trainer Bob Baffert's ban through 2024

Rescued Australian man who was adrift 3 months in Pacific with dog 'grateful' to be alive

ARCH Venture Partners tops STAT's 2023 biotech VC rankings

Leon Gautier, last member of French D

1 dead, 9 hurt in July 4th fireworks explosion

US recommends Americans reconsider traveling to China due to arbitrary law enforcement, exit bans

Wikipedia

Wikipedia

focus

After affirmative action ruling, medical educators look to 'holistic review'

Detailed data confirm benefits, risks of Eli Lilly's Alzheimer's drug

The cancer drug shortage isn’t new — and neither are the solutions

3 killed, 8 injured in late

At least 13 dead in Texas as scorching temps continue

Brazil's Neymar fined $3.3 million for illegal artificial lake at mansion outside Rio

Hollywood unions extend contract negotiations for actors

In early work, researchers turn to CRISPR to treat Alzheimer's

Medical leaders decry Supreme Court decision on affirmative action

AI can’t replace a physician’s gut feeling

focus

Kremlin open to talks over potential prisoner swap involving detained US reporter Evan Gershkovich

Doctors find melanoma drugs effective against rare brain cancer

Google and Epic fight stronger regulation of AI in health care

NASA releases new images of 'fingerprint

Whistleblower: Blue Cross Blue Shield evaded $170 million in taxes

Trump pressured former Arizona governor to overturn 2020 election results: Sources

hotspot

Wikipedia

hotspot

hotspot