entertainment -WSS

entertainment

author：Wikipedia 2025-09-29 01:35:03 - browse：82

The ability of cancer cells to move and spread depends on actin-rich core structures such as the podosomes (yellow) shown here in melanoma cells. Cell nuclei (blue), actin (red), and an actin regulator (green) are also shown. — Metastatic melanoma cells Julio C. Valencia,/NCI Center for Cancer Research

Nearly four decades after its first conception, the first TIL therapy, an immunotherapy that harvests cancer-fighting immune cells from the patient’s own body, received accelerated approval from the Food and Drug Administration for advanced melanoma. The therapy, called Amtagvi or lifileucel from Iovance, is the first cell therapy approved for a solid tumor.

“It’s so exciting and gratifying,” said Allison Betof Warner, a cell therapy researcher and physician at Stanford University who has worked on Amtagvi. “This is a game-changing moment for our field. We’ve seen huge success of cellular therapy for hematologic malignancies, and we’ve yet to capitalize on that for solid tumors. This is hopefully the first of many to come.”

In a Phase 2 clinical trial, titled C-144-01, 153 patients who had already been on a median of three prior lines of therapy received lifileucel, and 31% of them responded to therapy. “These are in very late line patients. They’ve exhausted every standard care option,” Betof Warner said. “The most promising part of this therapy for me is that 42% of patients who responded were still responding for 18 months or longer. It’s truly incredible.”

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Psychedelics group wrestles with new pharma identity
Next article： Most antidepressants don't work on kids, teens, study finds

hotspot

WSS

What Wagner Group's armed rebellion could mean for Russia's endgame in Ukraine

Black vets could get higher VA benefits if race not used in lung test

Most antidepressants don't work on kids, teens, study finds

Prince Harry seeks over $550,000 in phone hacking lawsuit against British tabloid publisher

Synthetic human embryos? Researchers say term is overblown

Federal board approves $12.7 billion budget for Puerto Rico as island shakes off bankruptcy

hotspot

entertainment

Wikipedia

In Memoriam: Notable people who died in 2023

HHS's proposed rule does nothing to address the climate crisis

Apple is now the first public company to be valued at $3 trillion

GSK’s asthma push continues as drug succeeds in Phase 3 trials

Food as medicine: CMS rules hamper 'prescribing' of fruits, veggies

Has Bernie Sanders reached the limit of his pharma bullying effort?

Malaria cases in Florida and Texas: Here’s what you need to know

Synthetic human embryos? Researchers say term is overblown

Heart attack and stroke risk calculators need revising

Empower primary care with adequate payments and technology

knowledge

GOP inquiry over gain

Sepsis can kill a child within hours. Here's how hospitals are fighting back

Here's how to stay safe from wildfire smoke amid reduced air quality

HHS's proposed rule does nothing to address the climate crisis

The sun may be out, but guns are not. A lawsuit challenges a new gun ban on Hawaii beaches

Empower primary care with adequate payments and technology

hotspot

explore

hotspot

focus