leisure time -WSS

leisure time

author：explore 2025-09-27 16:36:10 - browse：737

Seng Cheng has been working in gene therapy for nearly as long as gene therapy has been a field. As a young scientist in the early 1990s, he was part of one of three teams racing to develop a gene therapy for cystic fibrosis, a high-profile effort that resulted in national headlines, prestigious publications, and zero patients cured.

So he’s seen the field’s highs and lows. Lately, there have been a lot of both, including at Pfizer, the company Cheng called home until this summer. The pharma brought three potentially powerful gene therapies for muscular dystrophy and hemophilia into late-stage trials but, in January, chose to abandon a large portfolio of early stage candidates that relied on the same technology: adeno-associated viruses, or AAVs, a group of small bugs that scientists spent two decades taming into a gene shipping system.

The move seemed emblematic. Across the industry, AAV companies have been struggling, either shelving programs or stopping work altogether, while investors shuttled money toward new technologies such as CRISPR and its various permutations. Longtime researchers feared promising drugs, particularly for ultra-rare diseases, might get lost in the shuffle.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Cancer drug shortages should be causing more outrage
Next article： The drug industry sees a key ally in the Senate prevail

focus

WSS

OTC birth control: A brief history of over the counter pill design

Readout LOUD podcast: ESMO highlights & Roivant's big deal

What Henrietta Lacks settlement says about racism in medicine

Mega Millions jackpot rises to record $1.55 billion for Tuesday's drawing

Treeline, Josh Bilenker's next biotech, is cloaked in mystery

All of Us, NIH's precision medicine initiative, gets a big boost

hotspot

leisure time

focus

Trump demands the U.S. pay no more for drugs than other countries … again

All of Us, NIH's precision medicine initiative, gets a big boost

Cancer drug shortages should be causing more outrage

Verily hires former Apple Health leader as chief scientific officer

Bright Health sells Medicare Advantage business to Molina

ER docs worry over extreme heat as a 'mass casualty event'

Medical records are filled with copy

Gilgo Beach: Police identify another victim in serial killing investigation

As demand for Covid shots wanes, Moderna seeks its next success

Mega Millions jackpot rises to record $1.55 billion for Tuesday's drawing

Wikipedia

Lung cancer screening guidelines updated for cigarette smokers

Live blog: Hearing on CRISPR

Microsoft strikes partnership with Duke Health to advance health AI

Who is Magistrate Judge Moxila Upadhyaya in Trump's Jan. 6 case?

Infant mortality in U.S. rose last year for first time in decades: CDC

What is microchimerism and how does it affect maternal health?

hotspot

focus

explore

Wikipedia