knowledge -WSS

knowledge

author：hotspot 2025-10-01 14:59:28 - browse：61976

Alzheimer’s disease has killed at least three women in Astrida Schaeffer’s family over two generations, leaving her feeling helpless and bereft.

The first was her Polish-born maternal grandmother, who began showing symptoms when Schaeffer started college in 1981 and died seven years later. Then came her mother, a onetime Fulbright Scholar and high school language teacher who had been fluent in five languages but lost the ability to speak. She died in 2019. Last year, the disease killed Schaeffer’s mother’s sister, a former lab technician for Johnson & Johnson.

Schaeffer, a 59-year-old costume historian in North Berwick, Maine, has no symptoms of Alzheimer’s. But in 2021 her family history led her to apply to join a clinical trial testing a drug on people at risk for developing them. To participate, volunteers couldn’t have cognitive impairment. But they needed to test positive for a biomarker that put them at higher risk for mental decline ― deposits of a sticky toxic protein in the brain called beta-amyloid that is a hallmark of the disease.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Supreme Court strikes down use of affirmative action
Next article： Duchenne drug from Nippon Shinyaku fails in rare confirmatory trial

WSS

Richard Slayman had a rejection episode of his pig kidney before leaving hospital

In science, is the line between industry and academia shifting?

Medicare explains how it will choose drugs for negotiation

What do new weight loss drugs mean for bariatric surgery?

U.S. death rates show how politics are affecting public health

Psilocybin's anti

Wikipedia

knowledge

focus

The high cost of giving birth even with insurance

Study finds new variant for Parkinson’s in African populations

What does generative AI mean for health care? We asked experts

How Long Island became the ‘eugenics capital of the world’

Peter Hotez and the public health issue of online harassment

Complete sequence of Y chromosome published for first time

DIEP, the 'gold standard' of breast reconstruction, is under threat

Complete sequence of Y chromosome published for first time

The cancer drug shortage isn’t new — and neither are the solutions

Winners, losers from Medicare’s list of drugs subject to price talks

hotspot

The HPV vaccine prevents cancer in men, too. Why do so few people get it?

AstraZeneca bets AAV gene therapy will still deliver the goods

How to make Best Hospitals ratings actually useful for patients

Departing Stanford president retracts two papers

Apellis safety probe of eye disease drug centers on injection needle

J&J reports mixed data on next

explore

leisure time

hotspot

leisure time