Wikipedia -WSS

Wikipedia

author：knowledge 2025-09-14 18:30:54 - browse：8

Stock exchange — Drew Angerer/Getty Images

Structure Therapeutics reported Monday that its oral GLP-1 drug led to weight loss in two small studies, leading shares to surge in pre-market trading.

In a 12-week Phase 2a study, the daily pill in a capsule formulation led to 6.2% placebo-adjusted weight loss. In a separate 12-week pharmacokinetics study, the company tested a new tablet formulation of the drug, called GSBR-1290, and it led to placebo-adjusted weight loss of up to 6.9%.

Though it’s difficult to compare across different studies, the results appear to approach the levels of weight loss seen at 12 weeks in a separate Phase 2 study of Eli Lilly’s GLP-1 pill called orforglipron. That entire study lasted 36 weeks, but at 12 weeks, participants had about 6%-7% placebo-adjusted weight loss.

STAT+ Exclusive Story

Already have an account? Log in

This article is exclusive to STAT+ subscribers

Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

Already have an account? Log in

Monthly

$39

Totals $468 per year

$39/month Get Started

Totals $468 per year

Starter

$30

for 3 months, then $39/month

$30 for 3 months Get Started

Then $39/month

Annual

$399

Save 15%

$399/year Get Started

Save 15%

11+ Users

Custom

Savings start at 25%!

Request A Quote Request A Quote

Savings start at 25%!

2-10 Users

$300

Annually per user

$300/year Get Started

$300 Annually per user

View All Plans

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Malaria cases in Florida and Texas: Here’s what you need to know
Next article： What causes an itch? Researchers may have solved the mystery

focus

WSS

STAT Health News: mRNA flu shots, Purdue SCOTUS case, etc

SCOTUS to consider access to abortion pill mifepristone

Test for long Covid? Researchers find new clue in blood samples

Chemotherapy shortages won’t get better under Biden’s latest plan

FDA approves world's first CRISPR

After sickle

hotspot

Wikipedia

This article is exclusive to STAT+ subscribers

Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

knowledge

Indiana Supreme Court upholds abortion ban, says state constitution gives only limited protections

NIH director takes cautious approach to Biden drug pricing priority

Tori Bowie and the unacceptable rates of Black maternal death

Readout LOUD podcast: Biotech layoffs, stock slump, 2024 preview

What does generative AI mean for health care? We asked experts

What causes an itch? Researchers may have solved the mystery

United colonoscopy coverage change 'may cost lives,' doctors say

Readout Newsletter: BridgeBio, Madrigal, and Silicon Valley Bank

Activists slam private health insurers over coverage restrictions

Francis Collins on trust in science and how Covid communications failed

entertainment

Despite FDA approval for Lyfgenia, Bluebird faces stiff competition

What causes an itch? Researchers may have solved the mystery

In diabetes hearing, Sanders takes on a new foe: food makers

The woman behind the Dana Farber

Copay coupons to count toward deductibles, after Biden court move

The tragedy of Johnson & Johnson’s Covid vaccine

focus

hotspot

Wikipedia

explore