Wikipedia -WSS

Wikipedia

author：explore 2025-09-06 03:54:04 - browse：73334

Adam's take main illustration — Molly Ferguson/STAT

Anavex Life Sciences is in a tough spot. The serial dissembler of clinical trial results might be forced, finally, to tell the truth when it reads out its next study in Rett syndrome.

What sets Anavex apart from all the other biotechs on my radar screen is its habit of shifting the goalposts on clinical trials. Twice last year, first in February and then in December, Anavex announced “positive” outcomes from studies of its drug called blarcamesine — except the results were derived from efficacy endpoints that were not part of the original study designs.

If blarcamesine fails to achieve the pre-determined goals of clinical trials, the thinking apparently goes, then just make a post-hoc change to the study goals.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED Log In

Previous article： Peter Hotez and the public health issue of online harassment
Next article： Pfizer plans to depart BIO

hotspot

WSS

What PEPFAR has meant on the ground in Ukraine

Americans' trust in science, scientist continues decline: Report

Leukemia patients are helped by Syndax's new type of therapy

Wisconsin governor employs partial veto to fund schools for 4 centuries

Pregnancy discrimination could be enabled by AI

Dozens of beaches across Northeast closed for swimming due to high levels of bacteria in water

knowledge

Wikipedia

focus

How to save PrEP access — and even expand it

Giraffe named Twiga, who was among the oldest cared for by humans, died at age 31 at East Texas zoo

Medical leaders decry Supreme Court decision on affirmative action

Wisconsin governor employs partial veto to fund schools for 4 centuries

Peter Hotez and the public health issue of online harassment

Recent heat wave in the Mediterranean caused by climate change: Study

State Dept. review finds Biden bears some blame for Afghanistan failures

Pregnancy discrimination could be enabled by AI

Virginia high school admissions case could be legal follow

In diabetes hearing, Sanders takes on a new foe: food makers

Wikipedia

Dozens of beaches across Northeast closed for swimming due to high levels of bacteria in water

DeSantis defends odds vs. Trump, despite early poll gap: 'We've worked really hard'

Home health providers sue Medicare over payment cuts

STAT Health News: mRNA flu shots, Purdue SCOTUS case, etc

Presidential fundraising highlights so far: Trump brings in more than DeSantis

AI models in health care face new federal disclosure requirements

focus

explore

hotspot

knowledge