Wikipedia -WSS

Wikipedia

author：hotspot 2025-09-05 13:46:05 - browse：69

A follow-up study of a first-of-its-kind cancer treatment may reflect systemic biases, the Food and Drug Administration said ahead of an advisory committee meeting Thursday to determine whether the drug should remain on the market.

The treatment, Lumakras, is designed to treat lung cancer caused by a specific genetic mutation to a protein called KRAS. It’s one of the most common genetic mutations in cancer, but repeated clinical trial failures had led researchers to deem it “undruggable” until a glimmer of hope came about a decade ago.

Lumakras received an accelerated, or conditional, approval in May 2021, making it the first KRAS drug on the market. Now, the drug’s manufacturer, Amgen, needs to prove it works.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： BioMarin wins approval for gene therapy to treat hemophilia A
Next article： iTeos Therapeutics debuts first data on TIGIT

explore

hotspot

WSS

Latigo launches with $135 million for Vertex

Focused ultrasound for uterine fibroids: an uphill battle

Study gives hint on South Asians’ higher risk of cardiovascular disease

Childbirth

Juul documents reveal insider tactics on political lobbying

Childbirth

focus

Wikipedia

leisure time

Novavax promises a turnaround & Lilly roils the obesity market

Amylyx and the next ALS drug test, plus a chat with CRISPR's CEO

BioMarin wins approval for gene therapy to treat hemophilia A

Report cites 'urgent' need to recruit more diverse clinical trial participants

23andMe had bad news about my health. I wish a person had delivered it

Dark money group runs ads on China biotech bill

DIEP, the 'gold standard' of breast reconstruction, is under threat

Readout Newsletter: Replicate, Biogen's Leqembi, and Humira

Medical leaders decry Supreme Court decision on affirmative action

Latigo launches with $135 million for Vertex

explore

Average age of first period drops to 11.9 years, study shows

Addiction doctors spar with methadone clinics over legislation

Readout Newsletter: Moderna bird flu vaccine, Biohaven, ASCO

Sick patients collapsed waiting for care at Massachusetts hospital with known safety violations

Readout Newsletter: Replicate, Biogen's Leqembi, and Humira

Childbirth

explore

Wikipedia

hotspot

knowledge