Wikipedia -WSS

Wikipedia

author：Wikipedia 2025-09-05 07:00:21 - browse：79

An AstraZeneca sign at ESMO in Madrid. — An AstraZeneca ad at ESMO 2023 in Madrid. Andrew Joseph/STAT

MADRID — Questions about one of AstraZeneca’s key cancer drug candidates — and the dribs and drabs that have come out about its performance — have been dogging the company for months.

On Monday, data presented here from a trial of the drug in advanced non-small cell lung cancer provided at least a fuller look. While the results assuaged some of the safety fears that flared when initial information was released over the summer, they only heightened concerns about the drug’s ability to outperform standard chemotherapy — though they perhaps pointed to an opportunity for the drug in a subset of patients.

The trial, detailed here in a prime session at the annual meeting of the European Society for Medical Oncology, is testing a therapy called datopotamab deruxtecan, or Dato-DXd, in advanced or metastatic non-small cell lung cancer in patients who already tried at least first-line treatments. Patients were randomized to either receive chemotherapy or Dato-DXd, which AstraZeneca is developing with Daiichi Sankyo.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Malaria cases in Florida and Texas: Here’s what you need to know
Next article： NIH study of ME/CFS points to clear biological hallmarks

knowledge

WSS

Timeline: Special counsel's investigation into Trump's handling of classified documents

PBM reform efforts get punted in Congress

Who are the detained American citizens released from prison in Iran?

Iran moves toward freeing 5 American citizens who had been imprisoned, in rare deal

Readout Newsletter: Alnylam, Celldex, Roche, Zealand Pharma

Ed Silverman on new gene therapies, biosimilars, coffee, and more

hotspot

Wikipedia

entertainment

As demand for Covid shots wanes, Moderna seeks its next success

Trump, Nauta plead not guilty to new classified docs charges but De Oliveira still not arraigned

State Dept. review finds Biden bears some blame for Afghanistan failures

The perfect storm of weather conditions that led to the devastating wildfires in Maui

Hepatitis C has a cure — but many Americans still lack access to it

Where are patients getting their prescriptions for GLP

Trump demands the U.S. pay no more for drugs than other countries … again

Annovis Bio delivers candor, but not confidence, on Parkinson’s study

Walensky prepares to leave CDC — and Congress — behind

Annovis Bio delivers candor, but not confidence, on Parkinson’s study

Wikipedia

Presidential candidate assassinated in Ecuador, 1 suspect dead and 6 arrested

In utero gene editing: an explainer

Novo acquires Inversago for up to $1 billion

Readout Newsletter: Alnylam, Celldex, Roche, Zealand Pharma

Newly revealed memo details efforts to keep Trump in power following election loss

Covid's long

Wikipedia

knowledge

knowledge

hotspot