fashion -WSS

fashion

author：explore 2025-08-31 02:02:39 - browse：2

Adam's take main illustration — Molly Ferguson/STAT

The Food and Drug Administration should halt Cassava Sciences’ ongoing clinical trials in Alzheimer’s disease. That, and other thoughts on the fallout from the City University of New York investigation that raised serious doubts about the science underpinning the company’s experimental drug simufilam.

Patient safety is paramount to the FDA, so stopping Cassava’s two Phase 3 studies is the ethically correct thing to do.The FDA has the power to place clinical holds on experimental drugs when there’s evidence of an unacceptable safety risk to study participants. Simufilam doesn’t appear to be toxic. It’s not causing dangerous side effects. But study participants can also be harmed when they volunteer for a clinical trial based on false or misleading information about a drug’s potential efficacy.

The CUNY committee charged with investigating Cassava’s principal scientific collaborator, the neuroscientist Hoau-Yan Wang, could not definitively prove that Wang faked simufilam data, but that’s only because he refused to turn over original data and primary research records that the committee had requested to examine. Wang also claimed that boxes of research records relevant to the investigation were thrown away. The investigative report was first made public last week in the journal Science.

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： In age of alternative facts, a scholarly course on calling out crap
Next article： Novo Holdings to buy drug manufacturer Catalent in $16.5B deal

explore

WSS

Vyjuvek, a gene therapy for skin wounds, restored vision in one boy

Why do we get seasonal allergies?

The Biogen Aduhelm mess could happen again

Novo Holdings to buy drug manufacturer Catalent in $16.5B deal

The Biogen Aduhelm mess could happen again

Bernie brings in new pharma CEOs to talk drug prices

knowledge

fashion

hotspot

In Memoriam: Notable people who died in 2023

Prince Harry seeks over $550,000 in phone hacking lawsuit against British tabloid publisher

Guidelines to prevent youth baseball injuries need more muscle

AI gets buy

At least 13 dead in Texas as scorching temps continue

Belarusian journalist sentenced to 4 years in prison as crackdown continues

In Memoriam: Notable people who died in 2023

What’s missing from the debate over nursing home staff minimums

Continuity nursing helped my family in our darkest PICU moments

New lesbian bars spark hope amid disappearing LGBTQ+ spaces

focus

Prince Harry seeks over $550,000 in phone hacking lawsuit against British tabloid publisher

Novo Holdings to buy drug manufacturer Catalent in $16.5B deal

Lilly’s obesity pill cuts 15% of weight at highest dose in mid

The strange history of BMI, the body mass index

The strange history of BMI, the body mass index

Biden slams SCOTUS affirmative action decision: 'Discrimination still exists in America'

explore

knowledge

Wikipedia

explore