focus -WSS

focus

author：leisure time 2025-08-24 10:13:50 - browse：9647

Stoke Therapeutics is still seeking an effective dose for an experimental drug to treat a severe form of childhood epilepsy, following the release of updated data Tuesday that showed disappointing reductions in convulsive seizure activity.

In the latest look at an ongoing mid-stage study, three monthly injections of the Stoke drug, called STK-001, given at a 45-mg dose, resulted in a median 18% reduction in convulsive seizure activity, compared to baseline.

The new analysis was conducted on 16 children diagnosed with a rare form of epilepsy called Dravet syndrome. Last November, in six patients, the drug showed a median 55% reduction in seizure activity.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED Log In

Previous article： Bright Health sells Medicare Advantage business to Molina
Next article： Free medical tuition alone isn't enough to close gaps in primary care

WSS

Man pleads guilty to raping Ohio girl who ended up traveling across state lines for abortion

Readout Newsletter: Raw milk, Wegovy tests, Eisai and Biogen

Accuser says Kevin Spacey grope wasn't a caress: ‘It was like a cobra ... angry’

'Insanity': 4th of July mass shootings across US kill 13, injure more than 80

Novo Nordisk testing Wegovy against alcohol

5 shark bites reported on Long Island as officials deploy surveillance drones

hotspot

focus

entertainment

The Supreme Court will review a ruling striking down a domestic violence federal gun ban

Myanmar's Supreme Court hears arguments in 2 appeals by ousted leader Aung San Suu Kyi

United colonoscopy coverage change 'may cost lives,' doctors say

3 protesters arrested at Wimbledon after interrupting matches by throwing confetti on court

Guidelines to prevent youth baseball injuries need more muscle

'Insanity': 4th of July mass shootings across US kill 13, injure more than 80

Affirmative action in medical school literally saved lives

CVS is willing to dump 10% of its Medicare Advantage members

Heart attack and stroke risk calculators need revising

Adele warns fans about throwing things at performers onstage

focus

To spot an incipient stroke, tiny brain probe acts ‘like a microscope’

3 protesters arrested at Wimbledon after interrupting matches by throwing confetti on court

HHS suspends federal funding for EcoHealth Alliance

Search warrant issued in 1996 disappearance of Kristin Smart

Pentagon will tighten controls on classified information after Discord leak

STAT series 'Denied by AI' wins major journalism prizes

knowledge

leisure time

explore

knowledge