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                                      author：knowledge   
                                        
                                      
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          Zepbound, a injectable drug on a gradient background of dark purple and green — biotech coverage from STAT
          Illustration: STAT; Source: Eli Lilly/AP
          Eli Lilly’s blockbuster diabetes and obesity drug improved living scarring in a mid-stage study of the liver disease MASH, adding to positive data announced earlier this year.
          The study tested three doses of tirzepatide, sold commercially as Mounjaro or Zepbound. The percentage of patients who experienced a greater than one-stage improvement in scarring, or fibrosis, without worsening of their disease was ​​54.9%, 51.3%, and 51.0% from the lowest to highest doses.
          advertisement
          When compared with the 29.7% of patients on placebo who achieved this outcome, the results were statistically significant, according to an abstract of data that will be presented at the annual meeting of the European Association for the Study of the Liver.
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          Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.
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