Wikipedia -WSS

Wikipedia

author：comprehensive 2025-08-12 09:12:35 - browse：4814

Stock exchange — Drew Angerer/Getty Images

Structure Therapeutics reported Monday that its oral GLP-1 drug led to weight loss in two small studies, leading shares to surge in pre-market trading.

In a 12-week Phase 2a study, the daily pill in a capsule formulation led to 6.2% placebo-adjusted weight loss. In a separate 12-week pharmacokinetics study, the company tested a new tablet formulation of the drug, called GSBR-1290, and it led to placebo-adjusted weight loss of up to 6.9%.

Though it’s difficult to compare across different studies, the results appear to approach the levels of weight loss seen at 12 weeks in a separate Phase 2 study of Eli Lilly’s GLP-1 pill called orforglipron. That entire study lasted 36 weeks, but at 12 weeks, participants had about 6%-7% placebo-adjusted weight loss.

STAT+ Exclusive Story

Already have an account? Log in

This article is exclusive to STAT+ subscribers

Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

Already have an account? Log in

Monthly

$39

Totals $468 per year

$39/month Get Started

Totals $468 per year

Starter

$30

for 3 months, then $39/month

$30 for 3 months Get Started

Then $39/month

Annual

$399

Save 15%

$399/year Get Started

Save 15%

11+ Users

Custom

Savings start at 25%!

Request A Quote Request A Quote

Savings start at 25%!

2-10 Users

$300

Annually per user

$300/year Get Started

$300 Annually per user

View All Plans

Get unlimited access to award-winning journalism and exclusive events.

Subscribe Log In

Previous article： Hepatitis C has a cure — but many Americans still lack access to it
Next article： Trump's false claims about Georgia's 2020 election long debunked

WSS

Who gets to use the title 'doctor'?

FDA approves first treatment for ultra

4 killed in mass shooting in Georgia, shooter remains on the loose: Police

Michigan AG announces felony charges against 'fake electors' in 2020 election plot

Manchin, Huntsman team up to talk platform for 'unity' ticket that could run in 2024

New details revealed about Purdue's marketing of OxyContin

focus

Wikipedia

This article is exclusive to STAT+ subscribers

Unlock this article — plus daily coverage and analysis of the biotech sector — by subscribing to STAT+.

focus

The cancer drug shortage isn’t new — and neither are the solutions

Liz Cheney makes 1st public comment since Trump's election interference indictments

Trump demands the U.S. pay no more for drugs than other countries … again

The pain doctors face in trying to build their families

Jerome Adams on the need for new antivirals for Covid

American woman kidnapped in Mexico freed after 8 months in captivity: FBI

BioMarin wins approval for gene therapy to treat hemophilia A

Hilary may become 1st tropical storm to make landfall in California in 84 years

State Dept. review finds Biden bears some blame for Afghanistan failures

Evacuations in place as 3 wildfires burn in eastern Washington state

focus

4 killed in mass shooting in Georgia, shooter remains on the loose: Police

Ukraine taking heavy casualties 10 weeks into its counteroffensive

Woman gored by Bison at Yellowstone

Congress likely to miss an opportunity to fix drug shortages issue

Cancer drug shortages' outsize impact on ovarian cancer patients

Woman gored by Bison at Yellowstone

focus

leisure time

knowledge

knowledge